Stem cell Interventions for Joint Arthritis
• Among the chronic Joint pains, hip and knee osteoarthritis (OA) is the most prevalent and is a leading cause of pain and disability in most countries worldwide.
• The prevalence of arthritis increases with age and is associated with heavy occupational activities.
• 242 million people worldwide have symptomatic and activity-limiting arthritis of knee.
• Knee Osteoarthritis affects sleep, mood, and quality of life. Pain- both chronic pain and episodic- can result in depression and other mood disturbances, functional disabilities, and work limitations.
• OA significantly limits a person’s ability to self-manage other chronic diseases like diabetes and hypertension.
• Osteoarthritis knee also, increases the risk of developing heart disease by 50%.
Traditional nonsurgical Osteoarthritis therapies have limited utility and the the treatment effect on disease is very low. Most of the therapies are aimed at controlling the symptoms but have minimal or no effect on disease progression or repair. On the other hand, surgeries such as Total knee replacement and partial knee replacement is unwarranted until the disease progresses to moderate or end-stage.
Stem cell therapy by the Interventional Pain specialist has shown some promising results and has shown disease modification to prevent knee joint destruction. Stem cell therapy for knee arthritis has shown reduction of pain and stiffness, improvement in physical function, maintains cartilage quality with minimal side effects. Cost of the procedure and affordability is a matter of concern and may not be suitable for the masses.